Review article
https://doi.org/10.5513/JCEA01/23.4.3700
Probiotics and prebiotics in arterial hypertension
Mario IVANUŠA
orcid.org/0000-0002-6426-6831
; University of Rijeka, Faculty of Medicine, Braće Branchetta 20/1, Rijeka, Croatia
Marina PALFI
; Podravka Inc., Corporate Development, Ante Starčevića 32, Koprivnica, Croatia
Sara KNEŽEVIĆ
; University of Rijeka, Faculty of Medicine, Braće Branchetta 20/1, Rijeka, Croatia
Nada KNEŽEVIĆ
; Podravka Inc., Corporate Development, Ante Starčevića 32, Koprivnica, Croatia
Abstract
There is growing evidence that a disturbed microbiota, a complex ecosystem, is associated with the development of
numerous diseases, including arterial hypertension. This complex cardiovascular disease is the result of not sufficiently
clear role that genetic and environmental factors play in it. Not only does the treatment of hypertension include a
drug therapy, but also it includes a variety of non-pharmacological measures based on dietary intervention. Probiotics
and prebiotics are besides the nutrition the most commonly used substances that are aimed at maintaining a healthy
microbiome or restoring the balance in case of disturbed bacterial homeostasis in disease. Although many studies
have confirmed the effects of an imbalance in the gut microbiota (dysbiosis) in the last decade, the benefits of dietary
intervention with probiotics in people with hypertension need to be supported by stronger evidence and further clinical
trials in order to be ultimately confirmed.
Keywords
microbiota; probiotics; prebiotics; arterial hypertension
Hrčak ID:
288320
URI
Publication date:
21.12.2022.
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