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Gingival Papillomatosis as the Oral Sign of Cowden Syndrome: A Case Report

Ana Glavina ; Clinical Department of Oral Medicine, University Dental Clinic, Zagreb University Hospital Centre, Zagreb, Croatia
Mirna Bradamante ; Department of Dermatovenerology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Zagreb, Croatia
Merica Glavina Durdov ; nstitute of Pathology, Forensic Medicine and Cytology, University Hospital Split, School of Medicine, University of Split, Split, Croatia
Marinka Mravak-Stipetić ; Clinical Department of Oral Medicine, University Dental Clinic, Zagreb University Hospital Centre, Zagreb, Croatia; 2Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia


Puni tekst: engleski pdf 150 Kb

verzije

str. 260-264

preuzimanja: 129

citiraj


Sažetak

Cowden syndrome (CS) is a rare autosomal dominant, hereditary, multiorgan disease with higher risk for malignancies (breast, thyroid, endometrium). Mucocutaneous lesions occur in 90% of cases and are characterized by facial trichilemmomas, oral mucosal papillomas, and benign acral keratoses. We present the case of a 39-year-old female patient with the chief complaint of “white spots” on the upper and lower attached gingiva accompanied with skin changes on the face, hands, and soles. The patient’s family medical history revealed that her mother had an endometrial polyp and the sister had thyroid cancer. In the patient’s medical personal history she reported follicular thyroid adenoma, thyroid abnormalities (i.e. lymphocytic thyroiditis), fibrocystic changes and juvenile breast papillomatosis, lipoma, multiple fibromas, and genitourinary tumors. Based on extensive family and personal medical history, physical examination and histopathological findings, diagnostic criteria were fulfilled for the diagnosis of Cowden syndrome.

Ključne riječi

Cowden syndrome; gingival papillomatosis; multiple hamartoma syndrome

Hrčak ID:

290101

URI

https://hrcak.srce.hr/290101

Datum izdavanja:

20.11.2019.

Posjeta: 294 *