Review article
Dermatologic Adverse Events in Oncologic Therapies
Romana Čeović
orcid.org/0000-0002-1296-6174
; Department of Dermatology and Venereology, University Hospital Centre Zagreb, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Lovorka Kovačec
orcid.org/0009-0006-9603-728X
; University of Zagreb School of Medicine, Zagreb, Croatia
Zrinka Bukvić Mokos
; Department of Dermatology and Venereology, University Hospital Centre Zagreb, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Branka Marinović
; Department of Dermatology and Venereology, University Hospital Centre Zagreb, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Abstract
During recent decades, the number of patients diag-
nosed with cancer has been increasing. Conventional treatments,
which comprise chemotherapy, radiotherapy, surgery, and hor-
monal treatment, represent improvements in effectiveness and
safety of administration and continue to be the standard model
of treating malignancies. Advances in oncology have enabled the
development of newer therapies such as immunotherapy and
targeted therapy. However, numerous adverse events continue
to emerge, including dermatologic adverse events, which signifi-
cantly impact the course of treatment, treatment outcomes, and
patient quality of life. Alopecia occurs most commonly, along with
mucositis, xerosis, pruritus, hyperpigmentation, acral erythema,
nail changes, and many others. The early detection, monitoring,
and adequate treatment of these adverse events could prevent re-
duction, interruption, or permanent discontinuation of oncologic
therapies. Herein we review various dermatologic adverse events
that may occur due to the therapy applied, present their possible
treatments, and emphasize the need to evaluate their impact on
patient quality of life.
Keywords
cancer treatment; dermatologic adverse events; quality of life
Hrčak ID:
299673
URI
Publication date:
14.12.2022.
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