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https://doi.org/10.15836/ccar2023.130

Acute coronary syndrome due to intramural hematoma

Vlasta Soukup Podravec orcid id orcid.org/0000-0002-4605-0068 ; Bjelovar General Hospital, Bjelovar, Croatia
Kristina Milevoj Križić orcid id orcid.org/0000-0003-2115-3076 ; Bjelovar General Hospital, Bjelovar, Croatia
Ivana Petrović Juren orcid id orcid.org/0000-0002-2793-3455 ; Bjelovar General Hospital, Bjelovar, Croatia
Andreja Čleković-Kovačić orcid id orcid.org/0000-0002-4532-3597 ; Bjelovar General Hospital, Bjelovar, Croatia
Sandra Prša orcid id orcid.org/0000-0001-9639-3918 ; Bjelovar General Hospital, Bjelovar, Croatia


Puni tekst: engleski pdf 147 Kb

verzije

str. 130-130

preuzimanja: 79

citiraj

Preuzmi JATS datoteku


Sažetak

Ključne riječi

coronary intramural hematoma; acute coronary syndrome; coronary angiography

Hrčak ID:

301154

URI

https://hrcak.srce.hr/301154

Datum izdavanja:

27.4.2023.

Posjeta: 200 *



Introduction: Coronary intramural hematoma is defined as an accumulation of blood within the media of artery without intimal disruption. (1-4) It is a rare cause of acute coronary syndrome. Several factors such as the pre- and postpartum periods, trauma, hypertension, vasculitis, fibromuscular dysplasia, and the use of contraceptives may potentially relate to this phenomenon, yet this patient did not possess any of them. The most common profile is a middle-aged woman with few cardiovascular risk factors.

Case report: 60-year-old woman, smoker with history of untreated arterial hypertension, hyperlipidemia presented with retrosternal chest pain duration for 2 hours. Initial 12-lead electrocardiogram (ECG) showed elevated ST-segment in leads V4 to V6 and D1 and aVL. Patient received a loading dose of aspirin and ticagrelor and was transferred to a tertiary hospital for a coronary angiography which showed a subocclusively altered distal segment of the left anterior descending artery (LAD) up to the apex. Based on coronary angiography, it was concluded that it is most likely an intramural hematoma possibly caused by fibromuscular dysplasia. It was recommended to do a recoronarography in two months and to continue with dual antiplatelet therapy. A transthoracic echocardiogram showed normal global systolic function of the left ventricle with hypocontractility of the lateral wall. The patient was discharged after a few days in a very good condition. After two months recoronarography was performed which showed complete recanalization of the apical LAD. CT angiography of the renal arteries and supraaortic branches were also performed where no changes were found that would indicate fibromuscular dysplasia. The patient does not have chest pain anymore and she tolerates physical exertion well.

Conclusion: Diagnosis and treatment of intramural hematoma of the coronary artery is very challenging, because it is an overlooked diagnosis. Catheter-based angiography is validated for the diagnosis of coronary intramural hematoma. In a stable patient conservative approach is preferred because an intramural hematoma heals spontaneously. Dual antiplatelet therapy with aspirin and clopidogrel for one year is recommended followed by using aspirin alone indefinitely.

LITERATURE

1 

Moidy M, Al Kindi F. Coronary Intramural Hematoma: Challenges in Diagnosis and Management. Heart Views. 2019 January-March;20(1):17–20. https://doi.org/10.4103/HEARTVIEWS.HEARTVIEWS_15_19 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/31143382

2 

Fujikura H, Hata Y, Morino Y, Matsuzaki A, Oikawa K, Ikari Y, et al. Images in cardiovascular medicine. Acute coronary syndrome due to intramural hematoma. Circulation. 2006 December 19;114(25):e644–5. https://doi.org/10.1161/CIRCULATIONAHA.106.629162 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/17179027

3 

Alfadhli J, Alsharhan L, Martine C. Fibromuscular Dysplasia Presenting as Spontaneous Coronary Artery Dissection. J Cardiol Curr Res. 2017;9(2):00320. https://doi.org/10.15406/jccr.2017.09.00321

4 

Ndao SCT, Zabalawi A, Gilard M. Spontaneous coronary artery wall haematoma: success of conservative management despite alarming extension: a case report. Eur Heart J Case Rep. 2019 December;3(4):1–6. https://doi.org/10.1093/ehjcr/ytz159 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/31911971


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