Acta clinica Croatica, Vol. 61. No. 4, 2022.
Pregledni rad
https://doi.org/10.20471/acc.2022.61.04.15
Perinatal Aspects of SARS-CoV-2 Infection During Pregnancy: A Potential Cause for Concern
Ana Meyra Potkonjak
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Vesna Gall
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Danko Milošević
; Department of Pediatrics, Zagreb University Hospital Center, School of Medicine, University of Zagreb, Zagreb, Croatia; University of Zagreb, School of Medicine, Department of Pediatrics, Zagreb, Croatia
Vesna Košec
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Boris Filipović-Grčić
; Department of Pediatrics, Zagreb University Hospital Center, School of Medicine, University of Zagreb, Zagreb, Croatia; University of Zagreb, School of Medicine, Department of Pediatrics, Zagreb, Croatia
Sažetak
Ever since the beginning of COVID-19 pandemic, uncertainty regarding clinical
presentation and differences among various subpopulations exist. With more than 209,870,000
confirmed cases and more than 4,400,000 deaths worldwide, we are facing the new era of health crisis
which will undoubtedly impair global health, economic and social circumstances. In the past year,
numerous genetic mutations which code SARS-CoV-2 proteins led to the occurrence of new viral
strains, with higher transmission rates. Apart from the implementation of vaccination, the effect of
SARS-CoV-2 on pregnancy outcome and maternal fetal transmission remains an important concern.
Although neonates diagnosed with COVID-19 were mostly asymptomatic or presented with mild
disease, the effect on early pregnancy is yet to be evident. While positive finding of SARS-CoV-2
RNA in some samples such as amniotic fluid, placental tissue, cord blood and breast milk exists, additional
research should confirm its association with transplacental transmission.
Ključne riječi
SARS-CoV-2; COVID-19; Pregnancy; Vertical transmission; Neonates
Hrčak ID:
301976
URI
Datum izdavanja:
1.12.2022.
Posjeta: 495 *