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Nutrition, Body Weight and Deterioration of Familial Combined Hyperlipidemia

Judita Koprovičová
Jozef Kollár
Darina Petrášová


Puni tekst: engleski pdf 193 Kb

str. 777-782

preuzimanja: 456

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Sažetak

Lipid and apolipoprotein serum levels as a consequence of excessive nutrition in the overweight individuals with familial
combined hyperlipidemia (FCHL) in comparison with the obese ones are studied only sporadically. In this study,
the effect of overweight and obesity in subjects with FCHL on serum lipids and apolipoproteins was investigated. The
participants were 36 overweight and 10 obese men. 17 normolipidemic healthy men served as the control group. The
mean age of all subjects included was 49±9 years. Lipid and apolipoprotein serum levels were determined by standard
methods. The increased body weight in overweight men with FCHL correlates with increased cholesterol and triacylglycerol
serum levels (p<0.001), atherogenous ratio values, apolipoprotein serum levels – apo C-III, apo C-II and apo
B100 (p<0.001) as well as decreased HDL cholesterol serum levels (p<0.05). Lipid metabolism in men with FCHL is deteriorated
by a high energy intake and its low output. The overweight and not only obesity, in association with FCHL, is an
important risk factor for premature development of ischemic events.

Ključne riječi

overweight; obesity; hypercholesterolemia; hypertriacylglycerolemia; apolipoproteins; lipids

Hrčak ID:

27666

URI

https://hrcak.srce.hr/27666

Datum izdavanja:

13.12.2006.

Posjeta: 866 *