Izvorni znanstveni članak
Efficacy and Safety of Propofol Sedation During Urgent Upper Gastrointestinal Endoscopy – A Prospective Study
Neven Ljubičić
Vladimir Supanc
Goran Roić
Mirella Sharma
Sažetak
The aim of this study was to investigate both the efficacy and safety of sedation with
propofol during urgent therapeutic gastroscopy in patients with upper gastrointestinal
bleeding. This prospective study included a total of 110 patients. Propofol was administered
intravenously at the starting dose of 1 mg/kg body weight and was followed by repeated
doses. Oxygen saturation and heart rate were monitored by pulse oxymetry. The
mean dose of propofol administered was 161 49 mg. Urgent upper GI endoscopy under
propofol sedation was successful in 98% of cases. Endoscopists rated the sedation as
good in 83.6%, satisfactory in 14.5%, and poor in 1.8% of patients. Potentially harmful
drop in oxygen saturation below 85% was observed in 5.5% of patients, whereas a temporary
drop in heart rate below 50 beats/min was observed in 11.8%, not requiring any
intervention. Almost 93% of patients could not remember the beginning or the end of the
intervention. This data demonstrates that sedation with propofol is suitable for use in
patients with upper gastrointestinal bleeding undergoing urgent endoscopy.
Ključne riječi
gastrointestinal endoscopy; sedation; propofol
Hrčak ID:
28088
URI
Datum izdavanja:
16.6.2003.
Posjeta: 1.388 *