Izvorni znanstveni članak
Path Analysis of Familial Resemblance in Blood Pressure in Middle Dalmatia, Croatia
Tatjana Škarić-Jurić
Sažetak
The familial resemblance in blood pressure in Middle Dalmatia, Croatia, has been
analyzed using the Path-analytic approach. The sample consisted of 1,126 examinees
(526 males and 600 females, aged 17 to 87), inhabitants of the Middle Dalmatia’s islands
of Bra~, Hvar, Kor~ula and the Pelje{ac peninsula. The Path analysis was performed
with the assumption that each family member (father, mother, offspring 1 and 2)
has a latent variable (C) that influences both the blood pressure values (P) and the morphological
dimensions significantly correlated with blood pressure (Q). According to the
estimates revealed from the most parsimonious models, the diastolic blood pressure has
a more pronounced genetic component (h2 = 30–32%) than the systolic blood pressure (h2
= 15%). In contrast to the low intergenerational influences, the members of the same
generation showed pronounced effects of shared environment. Common (non-transmitted)
offsprings’ environment (B) explains 44% of variance of the individual offspring’s
environment (C) in systolic and 33–35% in diastolic blood pressure. The correlation of
father’s and mother’s environment (u2) was high in the case of diastolic blood pressure
(33–44%) but for the systolic blood pressure it was not significantly different from zero.
According to the presented results in insular/peninsular population of Middle Dalmatia,
family resemblance of systolic and diastolic blood pressure differs. The resemblance
is higher in diastolic blood pressure with stronger additive genetic component and
stronger environmental and/or genetic component related with morphology. The sources
of high heritability of diastolic blood pressure in Middle Dalmatia as well as the
sources of high prevalence of hypertension in the same population are the phenomena
that might be connected and thus deserve to be further explored in incoming analyses.
Ključne riječi
Path analysis; blood pressure; morphology; family; heritability; Croatia
Hrčak ID:
28103
URI
Datum izdavanja:
16.6.2003.
Posjeta: 743 *