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Role of Screening in Detection of Clinically Localized Prostate Cancer

Josip Galić
Ivan Karner
Ljiljana Ćenan
Antun Tucak
Željko Vranješ
Marijana Bilandžija-Peranović
Ivana Hegeduš

Puni tekst: engleski pdf 59 Kb

str. 49-54

preuzimanja: 354



The aim of this study was to confirm the role of screening by determining the percentage
of clinically localized prostate cancer (stage A and B) in patients with prostate cancer
detected on screening and in those presenting to urologic clinic for the symptoms of
urination impairment or ostalgia. During the study, 1,000 men aged 50 from the community
of ^epin and village of Josipovac near Osijek were examined. The subjects with
elevated concentration of total prostate specific antigen and/or digital rectal examination
suspect of carcinoma underwent transperineal biopsy of the prostate. Clinical staging
was performed in patients with prostate cancer detected on screening, and data on
clinical staging for prostate cancer patients treated during the 1996–1997 period were
retrieved from patient files of the Department of Urology, University Hospital »Osijek«.
On screening, 28 (80%) patients with localized prostate cancer and seven (20%) patients
with metastases were detected. In the group of patients examined on an outpatient basis
for the signs and symptoms of prostatism, there were 30 (83.4%) patients with metastases
and only six (16.6%) patients with localized prostate cancer. Study results indicated
that an early diagnosis of prostate cancer could be made by use of noninvasive
and inexpensive methods that cause no major discomfort to the patient. Accordingly,
these results appear to strongly support such screening in men, if not in all those aged
over 50, then at least in the otherwise healthy, 50–70 age group.

Ključne riječi

prostate cancer, screening, early detection

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