Acta clinica Croatica, Vol. 62. No. 1, 2023.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2023.62.01.03
Ultrasonographic Evaluation of Femoral Cartilage Thickness in Participants with Asymptomatic Hyperuricemia: A Case-Control Study
İlker Fatih Sari
orcid.org/0000-0003-0127-6503
; Giresun University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Giresun, Turkey
Fazıl Kulakli
; Giresun University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Giresun, Turkey
Nurçe Çilesizoğlu Yavuz
; Giresun University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Giresun, Turkey
İlker Ilhanli
orcid.org/0000-0002-7998-8992
; Ondokuz Mayıs University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Samsun, Turkey
Canan Çelik Içen
; Giresun University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Giresun, Turkey
Sažetak
The aim was to evaluate the effect, if any, of asymptomatic hyperuricemia on distal
femoral cartilage thickness through musculoskeletal ultrasonography. A total of 66 participants were
evaluated in this prospective, controlled study, including 33 asymptomatic hyperuricemic patients who
presented at our outpatient clinic between January and April 2020, and 33 normouricemic subjects
matched for age, gender and body mass index. Participants with systemic diseases affecting uric acid
level such as chronic renal failure, psoriasis, gout, etc., participants using drugs that can affect uric acid
level, and those with knee complaints were excluded from the study. Cartilage thickness measurements
were taken using musculoskeletal ultrasonography from the right medial condyle, right lateral
condyle, right intercondylar area, left medial condyle, left lateral condyle and left intercondylar area.
Distal femoral cartilage thickness was lower in all measurement areas in the asymptomatic hyperuricemia
group than in the normouricemic group (p<0.05 all). No correlation was noted between uric
acid levels and cartilage thickness in all measurement areas in either the asymptomatic hyperuricemic
or normouricemic group (p>0.05 all). We think that distal femoral cartilages seem to be thinner in
participants with asymptomatic hyperuricemia. Longitudinal studies are needed to determine whether
asymptomatic hyperuricemia will lead to knee osteoarthritis in individuals, although we believe
that people with asymptomatic hyperuricemia should be informed accordingly in order to prevent
development of potential knee osteoarthritis.
Ključne riječi
Asymptomatic hyperuricemia; Femoral cartilage; Osteoarthritis; Cartilage thickness; Ultrasound
Hrčak ID:
307134
URI
Datum izdavanja:
1.4.2023.
Posjeta: 411 *