Izvorni znanstveni članak
Event-Related Potentials in Medical Workers with Long-Term Exposure to Xylene
R. M. Liščić
Lj. Skender
J. Jakić-Razumović
D. Šimić
S. Milković-Kraus
Sažetak
The effects of chronic exposure to xylene on cognitive ability were studied in a group
of 35 medical workers occupationally exposed to low-level concentrations of xylene for at
least five years by using event-related potentials (ERPs), and compared with a control
group of 21 subjects. The exposure to xylene was confirmed through determination of
m-methylhippuric acid, a reliable biological indicator of xylene exposure, in pre- and
post-shift urine. A dose-effect relationship between log m-methylhippuric acid and ERP
log latency (p = 0.032), and the ERP amplitude (p = 0.047) was statistically significant.
The group of medical workers showed significantly longer ERP log latency (p < 0.001)
than did the control group with respect to factors of exposure to smoking, education and
age as covariates. For the ERP amplitude the difference was found not to be significant
(p = 0.263), probably due to high between subject variability. The cognitive impairment
may occur in workers chronically exposed to xylene.
Ključne riječi
Hrčak ID:
28346
URI
Datum izdavanja:
18.6.2001.
Posjeta: 1.020 *