Acta clinica Croatica, Vol. 62. No. 2, 2023.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2023.62.02.04
Serum Uric Acid to HDL Cholesterol Ratio Is Associated with Diabetic Control in New Onset Type 2 Diabetic Population
Mehmet Ali Kosekli
Gulali Aktas
orcid.org/0000-0001-7306-5233
Sažetak
Since uric acid to HDL cholesterol ratio (UHR) is proposed as a novel predictor of
metabolic and inflammatory disorders, we aimed to study UHR levels in patients with new onset type
2 diabetes mellitus (T2DM) and compare them to those in healthy controls. Patients with new onset
T2DM were enrolled and control subjects were volunteers to participate without any established diseases.
Laboratory data including UHR, fasting blood glucose (FBG) and glycated hemoglobin (HbA1c)
were compared. The mean UHR of the T2DM and control groups was 16±8% and 10±3%, respectively
(p<0.001). Moreover, UHR was significantly and positively correlated with HbA1c (r=0.75, p<0.001),
FBG (r=0.64, p<0.001), waist circumference (r=0.35, p<0.001), body mass index (r=0.20, p=0.002) and
inversely correlated with glomerular filtration rate (r=-0.24, p<0.001). High levels of UHR might be
associated with increased mean blood glucose levels for a long time, since UHR was correlated with both
FBG and HbA1c in patients with new onset T2DM.
Ključne riječi
Type 2 diabetes mellitus; Uric acid to HDL cholesterol ratio; HbA1c; Fasting blood glucose
Hrčak ID:
308635
URI
Datum izdavanja:
1.8.2023.
Posjeta: 374 *