Izvorni znanstveni članak
https://doi.org/10.20471/acc.2023.62.s2.15
Management of Prostate Cancer in Kidney Transplant Recipients
Zoran Zimak
orcid.org/0000-0002-3776-8203
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Ivica Mokos
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Hrvoje Saić
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Dinko Hauptman
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Milko Padovan
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Tvrtko Hudolin
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia
Eleonora Goluža
; University of Zagreb School of Medicine, Zagreb, Croatia; Department of Anesthesiology and ICU, Zagreb University Hospital Center, Zagreb, Croatia
Nikolina Bašić Jukić
orcid.org/0000-0002-0221-2758
; University of Zagreb School of Medicine, Zagreb, Croatia; Department of Internal Medicine, Zagreb University Hospital Center, Zagreb, Croatia
Željko Kaštelan
; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia; Croatian Academy of Science and Arts, Zagreb, Croatia
Sažetak
Kidney transplantation is the treatment of choice in eligible patients with end-stage
kidney disease. Prostate cancer (PC) is the second most common cancer in men worldwide. The prevalence
of chronic kidney disease worldwide is 13.4%. The management of localized PC in these patients
is challenging due to immunosuppressive therapy and pelvic graft localization. High graft and recipient
survival rates have resulted in higher numbers of these patients in our everyday practice. A retrospective
analysis of male patients who had undergone kidney transplantation at our center between 2002 and
2022 and were diagnosed and treated for PC was performed. We analyzed the incidence, treatment
methods, and follow-up of PC patients in this population. A total of 1079 male patients were transplanted.
PC was diagnosed in 12 patients (8 after and 4 before transplantation). The incidence of PC
was 1.11%. Radical prostatectomy was performed in 11 patients, and one patient was treated with radical
radiotherapy. Eleven patients had stable graft function; 1 graftectomy was performed, unrelated to PC.
Three patients were indicated for salvage radiotherapy, one is in process for prostate-specific membrane
antigen positron emission tomography (PSMA PET CT), and 7 patients are in follow-up and without
recurrence. Radical prostatectomy is a safe treatment method for localized PC in kidney transplant recipients,
which does not impair graft function and survival.
Ključne riječi
Prostate cancer; Kidney transplantation; Radical prostatectomy
Hrčak ID:
309994
URI
Datum izdavanja:
31.7.2023.
Posjeta: 185 *