Skoči na glavni sadržaj

Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, Vol. 559 No. 64-65, 2023.

Studija slučaja

https://doi.org/10.21857/m3v76t5eqy

Non-steroidal anti-inflammatory drugs exacerbated respiratory disease – a condition overlooked by anesthesiologist

Tea Pašalić ; Klinički bolnički centar Zagreb, Klinika za anesteziologiju, intenzivnu medicinu i liječenje boli,Zagreb, Hrvatska *
Anja Mandarić ; Klinički bolnički centar Zagreb, Klinika za anesteziologiju, intenzivnu medicinu i liječenje boli,Zagreb, Hrvatska
Marijana Žura ; Klinički bolnički centar Zagreb, Klinika za anesteziologiju, intenzivnu medicinu i liječenje boli,Zagreb, Hrvatska
Zrinka Orešković ; Klinički bolnički centar Zagreb, Klinika za anesteziologiju, intenzivnu medicinu i liječenje boli,Zagreb, Hrvatska
Sandra Morović ; Arsano Medical Group, Zagreb, Hrvatska

* Dopisni autor.

Puni tekst: engleski pdf 161 Kb

str. 102-105

preuzimanja: 182

citiraj

Sažetak

NSAID-exacerbated respiratory disease (N-ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis with nasal polyps (CRNwNP), symptoms of which are exacerbated by NSAIDs, including acetylsalicylic acid (ASA). The clinical reaction to NSAID develops within 30-180 min and it is manifested by upper and/or lower airway symptoms. The majority of N-ERD patients suffer from moderate to severe asthma. A diagnosis
of N-ERD is fundamentally based on the patient’s history. N-ERD is suspected in patients having a history of upper/lower respiratory reactions after ingestion of ASA/NSAIDs or suffering from asthma along with chronic rhinosinusitis and nasal polyps. In this paper 57 years old women with history of well controlled asthma, allergic rhinitis and allergy to ASA is presented. After surgical procedure of total knee arthroplasty, during intensive care unit (ICU) stay, ketoprofen was administrated. Soon after, the patient develops symptoms such as dyspnea with decreased oxygen saturation (SpO2) and heaviness in stomach followed by appearance of swelling and itching of elbows and feet. After administrated therapy patient’s condition was improved. NSAIDs are frequently used analgesics and antipyretics that should be used with caution in patients who suffer from asthma.

Ključne riječi

Acetylsalicylic acid; Asthma; Chronic rhinosinusitis with nasal polyps; Non steroidal anti-inflammatory drugs exacerbated respiratory disease

Hrčak ID:

312747

URI

https://hrcak.srce.hr/312747

Datum izdavanja:

22.12.2023.

Posjeta: 480 *