Case report, case study
https://doi.org/10.21857/mzvkptlq29
Case report of patient with SARScov- 2 infection, encephalopathy and psychiatric comorbidity
Iva Mihaljević
; Department of Neurology, University Hospital Dubrava, Zagreb, Croatia
Antonija Mahmutović
; Department of Neurology, KlinikLandstrasse, Wien, Austria,
Stela Bukvić
; Department of Neurology, University Hospital Dubrava, Zagreb, Croatia
Marko Tomičević
; Clinic of Psychiatry, Clinical Hospital Dubrava, Zagreb, Croatia
Martina Blažev
; Clinic of Psychiatry, Clinical Hospital Dubrava, Zagreb, Croatia
Ivana Šušak Sporiš
; Department of Neurology, University Hospital Dubrava, Zagreb, Croatia
Davor Sporiš
; Department of Neurology, University Hospital Dubrava, Zagreb, Croatia
Abstract
Neurological and neuropsychiatric manifestations of the coronavirus disease 2019 (COVID-19) have
been widely described, but yet the pathophysiology underlying these presentations is still unclear.
COVID-19 encephalopathy is a common neurological manifestation of SARS-CoV-2 infection and
has been associated with poorer outcomes so it is crucial to be recognized early for further decision
making regarding medical procedures and treatment. That can be challenging since the brain MRI
scan can be normal or nonspecific as well as the EEG reports and analysis of cerebrospinal fluid is unremarkable.
It is especially challenging in patients with a prior psychiatric diagnosis because symptoms
can overlap
We present the case of COVID-19 associated acute encephalopathy in patient with a history of organic
delusional disorder who presented with symptoms of delirium, minimal speech production which
progressed to mutism and stupor.
Due to the wide range and overlapping of clinical presentation, nonspecific diagnostic findings and
unclear therapeutic goal retrospectively, multidisciplinary approach is important in patients with neuropsychiatric
manifestation of SARS-CoV-2 infection.
Further investigation is paramount in order to determine the potential central nervous system effects
of infection with SARS CoV 2 and the optimal therapeutic approach.
Keywords
COVID-19, SARS-CoV-2, Delirium, Encephalopathy, Mutism
Hrčak ID:
312752
URI
Publication date:
22.12.2023.
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