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Professional paper

https://doi.org/10.57140/mj.53.4.8

Multifocal metachronous occurence of different hystologic sinonasal-type papilloma: a case report

Jakov Ajduk ; KBC Sestre milosrdnice, Klinika za otorinolaringologiju i kirurgiju glave i vrata; Medicinski fakultet Sveučilišta u Zagrebu
Mirta Peček ; Medicinski fakultet Sveučilišta u Zagrebu
Marija Pierobon ; Medicinski fakultet Sveučilišta u Zagrebu
Iva Mažić ; Medicinski fakultet Sveučilišta u Zagrebu
Tomislav Gregurić ; KBC Sestre milosrdnice, Klinički zavod za dijagnostičku i intervencijsku radiologiju
Andro Košec ; KBC Sestre milosrdnice, Klinika za otorinolaringologiju i kirurgiju glave i vrata; Medicinski fakultet Sveučilišta u Zagrebu


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Abstract

Introduction: Sinonasal-type papilloma is a very rare tumor, most commonly connected with the
sinonasal space, and very rarely with the middle ear. Primary tumors of the temporal bone are extremely
rare and only 28 cases have been described in literature, with additional 29 cases of tumor spreading from
the sinonasal tract to the temporal bone.
Case presentation: We discuss the case of a 49-year-old woman who had a primary right-sided
exophytic form of the sinonasal papilloma of the middle ear, which led to right-sided hearing loss, aural
fullness, and otorrhea. During postoperative CT and MRI follow-up one year after surgery, a sinonasal
oncocytic-type papilloma was discovered in the sphenoid sinus. To our knowledge, this is the first described
case of histologically two different primary sinonasal-types of papilloma in a patient. Common presenting
symptoms associated with sinonasal papilloma of the middle ear can be easily misdiagnosed with chronic
otitis media or Eustachian tube dysfunction. Although primarily benign, sinonasal papillomas are locally
aggressive and pose a risk of recurrence and malignant transformation. Therefore, surgery remains the
treatment of choice with necessary long-term follow-up, to detect relapse or even a completely new tumor
in that area.

Keywords

exophytic type; middle ear; papilloma; sinonasal papilloma; sphenoid sinus; temporal bone

Hrčak ID:

313419

URI

https://hrcak.srce.hr/313419

Publication date:

16.1.2024.

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