Stručni rad
Hypersensitivity Reactions to Homemade Topical Preparations
Mislav Rončević
orcid.org/0009-0005-7846-5558
; University of Zagreb, School of Medicine, Zagreb, Croatia
Katarina Radas
orcid.org/0009-0001-9032-3932
; University of Zagreb, School of Medicine, Zagreb, Croatia
Suzana Ljubojević Hadžavdić
orcid.org/0000-0002-3640-9567
; University of Zagreb, School of Medicine, Zagreb, Croatia
Sažetak
ABSTRACT Homemade topical preparations are becoming increas-
ingly popular due to the widespread belief that herbal and natural
products are a safer and better option in the treatment of various
conditions. However, homemade topical preparations can precipitate
allergic and irritant reactions, depending on the herbal composition
of the preparation. Hypersensitivity reactions to such preparations
range from contact allergic dermatitis, contact irritant dermatitis,
contact urticaria, toxic reaction, photosensitivity, and phototoxic re-
action. In Europe, and especially in the Mediterranean area, medicinal
herbs from the Compositae family and aromatic Mediterranean herbs
are most frequently used in the formulation of topical preparations.
Although plants are regarded as strong sensitizers, the number of re-
ported cases of hypersensitivity reactions is relatively small. The prob-
lems are limitations in diagnostics due to the lack of necessary patch
test substances and the danger of active sensitization during testing.
Caution is required in patients prone to allergies and those with exist-
ing dermatoses, who should be advised to use registered prepara-
tions. The first step in management is cessation of exposure, followed
by implementation of topical corticosteroids. Systemic corticosteroid
therapy is reserved for more severe cases.
Ključne riječi
homemade preparations; Compositae family; Lamiaceae family; hypersensitivity reaction
Hrčak ID:
316428
URI
Datum izdavanja:
15.9.2023.
Posjeta: 0 *