Stručni rad
The Association Between Hidradenitis Suppurativa and Diet: An Update
Marko Belamarić
; Health Center “Zagreb – Centar”, Zagreb, Croatia
Joško Miše
; Department of Dermatology and Venereology, University Hospital Centre Zagreb, Zagreb, Croatia
Zrinka Bukvić Mokos
; School of Medicine University of Zagreb, Zagreb, Croatia
Sažetak
Hidradenitis suppurativa (HS) is a chronic inflammatory skin
condition characterized by painful inflammatory lesions, predominantly
affecting areas of the skin rich in apocrine glands, such as inguinal, ax-
illary, submammary, and anogenital regions, with an estimated global
prevalence between 1%-4%. The treatment of HS is challenging with
various treatment modalities employed to control the disease. Since the
condition is chronic and life-impairing, many patients have looked for
ways to complement their conventional treatment procedures with non-
medical interventions, among which dietary interventions have been
of particular interest. Researchers have looked for ways to connect the
gastrointestinal system with the skin through the ̋skin-gut axis concept ̋
introducing a strong association between the microbiome of the gastro-
intestinal system and the skin. In addition, diet stimulation of insulin and
IGF-1 (insulin-like growth factor 1) may impact signaling pathways play-
ing a role in HS pathogenesis. Patients have tried various dietary inter-
ventions to alleviate their symptoms of inflammation and suppuration.
Among the different dietary approaches that have been described are
paleo, autoimmune, Mediterranean, and elimination diet regimes. Di-
etary supplements have become the mainstay of lifestyle factors aimed
at improving the clinical signs and symptoms of HS. This review aims to
synthesize and present the current findings on diet as a modifiable fac-
tor in HS, helping the patients to navigate through the data and helping
them make informed choices on their healthy lifestyles.
Ključne riječi
hidradenitis suppurativa; skin-gut axis; diet; dietary sup- plements
Hrčak ID:
316457
URI
Datum izdavanja:
15.12.2023.
Posjeta: 0 *