Stručni rad

Methemoglobinemija uzrokovana akcidentalnom intoksikacijom metolaklorom i metobromuronom

Branimir Anić
Stjepko Pleština
Radovan Radonić
Marina Vidović
Dubravka Bosnić

Sažetak

An 81-year-old man was admitted in the emergency department approximately four hours after accidental ingestion of an unknown quantity of herbicide »Galex 500 EC«. This product contains 25% of metolachlor and 25% of metobromuron dissolved in xylene. In spite of the fact that the combination of aniline and urea-substituted derivatives is widely used in agriculture as herbicide, there are very few data available about their harmful effects on humans. These agents appear to be mildly toxic, and rarely has a major systemic effect been reported after the poisoning. On admittance, our patient showed remarkable cyanosis and his methaemoglobin level was 38.4% of the total haemoglobin, rising next day to 46.2%. Only mild transient signs of hypoxic effects on central nervous system were observed and the laboratory findings indicated mild haemolysis. Methylene blue was applied intravenously in a dose of 1.5 mg/kg (10 ml, 1% solution) on the second day of admission. Administration of methylene blue was very effective and the patient was discharged from the hospital fully recovered.

Ključne riječi

akcidentalna intoksikacija; akcidentalno otrovanje; Galex 500 EC; herbicid; methemoglobinemija; metilensko modrilo; metolaklor; metobromuron

Hrčak ID:

2761

URI

https://hrcak.srce.hr/2761

Datum izdavanja:

9.9.1999.

Podaci na drugim jezicima: engleski

Posjeta: 6.082 *