Izvorni znanstveni članak
https://doi.org/10.26332/seemedj.v7i2.284
Sex-Related Differences in Characteristics and Therapy of Heart Failure Patients
Željka Dragila
; Department of Emergency Medicine, University Hospital Center Osijek, Osijek, Croatia; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
*
Lea Gvozdanović
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Emergency Medicine, General Hospital Našice, Našice, Croatia
Romana Marušić
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Internal Medicine, National Memory Hospital Vukovar, Vukovar, Croatia
Lana Maričić
; Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Cardiology, Department of Internal Medicine, University Hospital Center Osijek, Osijek, Croatia
* Autor za dopisivanje.
Sažetak
Aim: To determine the differences in comorbidities, therapy and echocardiographic measures among patients hospitalized for heart failure relative to gender.
Methods: The study included patients hospitalized for heart failure at the Department of Cardiovascular Diseases of the Clinical Hospital Center Osijek in the period from 1 January 2020 to 30 March 2021.
Results: There were 200 patients included in the study, of which 100 (50%) were male and 100 (50%) were female. Female patients were older, while male patients more frequently had a history of coronary artery disease. Men had a higher dose of loop diuretic on admission to the hospital. No significant difference was found in the representation of beta blockers and ACE inhibitors in therapy with regard to gender. On the other hand, men more frequently used MRA, sacubitril/valsartan and antiplatelet medication at hospital admission. Male patients had a larger left ventricular end-diastolic diameter, left ventricular end-systolic diameter and a lower left ventricular ejection fraction (EF). Regarding the type of heart failure according to EF, 72% of men had HFrEF, 20% HFmrEF and 8% HFpEF. In women, 47% had HFrEF, 33% HFmrEF and 20% HFpEF. During hospitalization due to heart failure, 22 patients died, an equal number of men and women.
Conclusion: This research confirmed the differences in risk factors and pathophysiology of heart failure between males and females. Medicine is progressing towards an individual approach to each patient, so further research will be needed to find the best therapy for both male and female patients.
Ključne riječi
ejection fraction; heart failure; sex characteristics; therapy
Hrčak ID:
319406
URI
Datum izdavanja:
19.7.2024.
Posjeta: 0 *