Izvorni znanstveni članak
https://doi.org/10.20471/LO.2024.52.01.03
Histopathological study of solitary thyroid nodules in a sample of Iraqi patient
Ghufran Ali-Jasim
; College of Medicine, University of Baghdad, Baghdad, Iraq
*
Sazan Abdulwahab-Mirza
; Pathology, College of Medicine, University of Baghdad, Baghdad, Iraq
* Dopisni autor.
Sažetak
Objectives: To examine solitary thyroid nodules and their behavior, clinicopathological characteristics, age, sex, ultrasonography, Thyroid Imaging Reporting & Data System results (TIRADS), and cytological groupings (Bethesda).
Methods: A retrospective study includes 100 solitary thyroid nodules from archives of Medical city labs between 2021 and 2023. TIRADS and Bethesda categories were recorded when accessible. Radiology records were provided for 98 patients and cytology for 21.
Results: The average age of patients was 37.5±11.8 years, with a male-to-female ratio of 1:4.7. The nodules were 67% benign, 22% malignant, and 11% low-risk. The most prevalent pathological diagnosis of single nodules was colloid nodules (45%) followed by papillary carcinoma (16%). Twenty-two present of single thyroid nodules were malignant, all were well-differentiated. In ultrasonography, TIRADS classifications 3-5, malignancy risk was 4.7%, 30.8%, and 53.3%. The risk of malignancy for Bethesda 2-5 was 0, 14.3%, 25%, and 100%. All malignancies were in adults with 1:4.5 female predilection. No significant association was seen in patient’s age, sex, or nodule side. Ultrasound had greater sensitivity (90.9% vs 85.7%), while cytology was more specific (76.9% vs 64.6%) and had a larger positive predictive value (66.7% vs 46.5%). Cytology was more accurate than ultrasonography (80% vs 71.3%).
Conclusion: There was a 22% risk of cancer in solitary thyroid nodules, all were well-differentiated. Bethesda was more precise, while ultrasound was more sensitive.
Ključne riječi
thyroid; solitary nodule; risk of malignancy; Bethesda; TIRADS
Hrčak ID:
320738
URI
Datum izdavanja:
16.9.2024.
Posjeta: 247 *