Review article

Anticoagulants – A Guide for Clinical Practice

Hrvoje Roguljić

Abstract

Oral anticoagulants (VKA and DOAC) are a diverse group of drugs with different pharmacokinetic and pharmacodynamic properties. Patient characteristics such as age, weight, comorbidities (especially renal function) and concomitant therapy have a significant effect on the efficacy and safety profile of this class of drugs. Given that this is a widely used group of drugs that carries with it the risk of bleeding, possibly even fatal, in clinical work there are often doubts about the type and dose of the appropriate anticoagulant. The aim of this paper is to show the most common clinical doubts and problems in the treatment of patients with oral anticoagulants, as well as the appropriate response to the most common complication of this therapy - bleeding.

Keywords

oral anticoagulants; warfarin; DOAC; bleeding

Hrčak ID:

321778

URI

https://hrcak.srce.hr/321778

Publication date:

24.10.2024.

Article data in other languages: croatian

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