Izvorni znanstveni članak
https://doi.org/10.20471/acc.2024.63.s2.2
Evaluation of Prostate Imaging Reporting and the PI-RADS Version 2 Data System for Prostate Cancer Detection: a Retrospective Single-Center Study
Lora Grbanović
; Department of Radiology, University Hospital Centre Zagreb, Zagreb, Croatia
Lucija Kovačević
orcid.org/0000-0002-2132-9636
; Department of Radiology, University Hospital Centre Zagreb, Zagreb, Croatia
*
Tomislav Kuliš
; Department of Urology, University Hospital Centre Zagreb, Zagreb, Croatia
Željko Kaštelan
; Department of Urology, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb University of Zagreb, Zagreb, Croatia
Marko Kralik
; Department of Radiology, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb University of Zagreb, Zagreb, Croatia
Stjepan Ivandić
; Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Maja Prutki
; Department of Radiology, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb University of Zagreb, Zagreb, Croatia
* Dopisni autor.
Sažetak
This retrospective study aimed to evaluate the performance of multiparametric
MRI (mpMRI) interpreted according to the Prostate Imaging Reporting and Data System (PIRADS)
version 2 (v2) in detecting clinically significant prostate cancer (csPCa). The study included
62 patients with a clinical suspicion of prostate cancer who underwent mpMRI of the prostate interpreted
according to the PI-RADS v2 between January 2018 and December 2018. Histopathologic
findings were considered positive if csPCa was found; otherwise, clinical follow-up of at least 4 years
was required to rule out the presence of csPCa. Diagnostic accuracy of PI-RADS v2 was calculated
using score cutoffs of 3 and 4. Out of 114 lesions detected on mpMRI, 21 were identified as csPCa.
The detection rates of PI-RADS scores 1-5 for detecting csPCa were 0%, 5.1%, 8.3%, 47.1%, and
87.5%, respectively. PI-RADS ≥4 cutoff yielded higher specificity (83.9%) and positive predictive
value (93%) for detecting csPCa than PI-RADS ≥3 (specificity 41.9%; positive predictive value 26%),
but exhibited lower sensitivity (71.4% versus 90.5%, respectively) and missed 28.6% of csPCa. In conclusion,
better csPCa detection with PI-RADS v2 cutoff set at 3 comes at the cost of lower specificity
and more unnecessary biopsies.
Ključne riječi
Prostatic neoplasms; Multiparametric magnetic resonance imaging; PI-RADS
Hrčak ID:
322859
URI
Datum izdavanja:
30.4.2024.
Posjeta: 0 *