Veterinarska stanica, Vol. 56 No. 5, 2025.
Pregledni rad
https://doi.org/10.46419/vs.56.5.9
Dynamics between cerebrospinal fluid and aqueous humour – are they bidirectional?
Marija Mamić
; Faculty of Veterinary Medicine University of Zagreb, Croatia
*
Mihovil Matković
; Faculty of Veterinary Medicine University of Zagreb, Croatia
Petra Dmitrović
; Faculty of Veterinary Medicine University of Zagreb, Croatia
Valentina Plichta
; Faculty of Veterinary Medicine University of Zagreb, Croatia
Boris Pirkić
; Faculty of Veterinary Medicine University of Zagreb, Croatia
* Dopisni autor.
Sažetak
The ophthalmology examination is crucial for the treatment of certain systemic diseases. The eye is an anatomical extension of the brain, and many similarities can be found between them. Multidisciplinary research of the brain or the eye will cross-fertilise each other, especially in the context of neurodegenerative diseases. As an extension of the telencephalon, the optic nerve is surrounded by the meninges and cerebrospinal fluid, just like the brain. Numerous studies and hypotheses have focused on the movement of cerebrospinal fluid in this region, particularly the influence of pressure on this area and the translaminar pressure gradient that develops as a result of this pressure. In the 1970s, Volkov proposed the theory that glaucoma is a two-pressure disease, which was supported by studies on astronauts, who often exhibit visual disturbances with swelling of the eye disc. Understanding the balance between intraocular pressure, cerebrospinal fluid pressure, and systemic blood pressure is key to better management of diseases such as glaucoma and intracranial hypertension. The aim of this article was to re-evaluate the current state of knowledge in order to improve the treatment of pathological conditions resulting from disturbances in aqueous humour and cerebrospinal fluid flow.
Ključne riječi
CSF dynamics; eye; glaucoma; lamina cribrosa; optic nerve
Hrčak ID:
326190
URI
Datum izdavanja:
3.4.2025.
Posjeta: 0 *