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https://doi.org/10.15836/ccar2024.376

A patient with a rare mechanical complication of myocardial infarction - ischemic ventricular septal defect: a case report

Nikolina Mijač Mikačić orcid id orcid.org/0000-0002-0933-6577 ; Zabok General Hospital and Hospital of Croatian Veterans, Zabok, Croatia
Siniša Roginić orcid id orcid.org/0000-0002-0384-8088 ; Zabok General Hospital and Hospital of Croatian Veterans, Zabok, Croatia
Alan Hodalin orcid id orcid.org/0009-0003-3619-3342 ; Magdalena Clinic for Cardiovascular Diseases, Krapinske Toplice, Croatia
Tereza Knaflec orcid id orcid.org/0000-0002-4915-3935 ; Zabok General Hospital and Hospital of Croatian Veterans, Zabok, Croatia
Iva Zec orcid id orcid.org/0000-0002-7947-3577 ; Zabok General Hospital and Hospital of Croatian Veterans, Zabok, Croatia
Martina Roginić orcid id orcid.org/0000-0001-5463-5392 ; Zabok General Hospital and Hospital of Croatian Veterans, Zabok, Croatia


Puni tekst: engleski pdf 153 Kb

str. 376-376

preuzimanja: 116

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Sažetak

Ključne riječi

ST-elevation myocardial infarction; ventricular septal defect; mechanical complication

Hrčak ID:

327756

URI

https://hrcak.srce.hr/327756

Datum izdavanja:

13.12.2024.

Posjeta: 308 *



Introduction: Mechanical complications of myocardial infarction are very rare due to reperfusion therapy (1). Postischemic ventricular septal defect (VSD) is the most common mechanical complication occurring in less than 1% of patients, primarily in those with ST-elevation myocardial infarction (STEMI) (2). This is an emergency condition with high mortality, which requires urgent cardiac surgery (3).

Case report: We present 63-year-old female patient, smoker with obesity who at the Emergency Department with non-specific symptoms such as vomiting, diarrhea and upper abdominal pain which radiates to the back. Later it was revealed that she had chest pain and dyspnea during physical activities for the past 15 days. Clinical examination showed systolic precordial murmur (III/VI) with symptoms of heart failure with tachypnea (26/min). Electrocardiographic findings were subacute myocardial infarction with ST elevation in the anteroseptal region. Laboratory tests confirmed elevated cardiac-specific enzymes with a downward trend after one hour. Also liver lesion was found. Chest X-ray showed acute congestion changes and right pleural effusion. Urgent echocardiography showed normal sized of concentric hypertrophic left ventricle with hypokinesis of middle segment of anteroseptal wall and akinesia of apex. In distal segment of interventricular septum was found VSD (9 mm in diameter) with left to right shunt. Ejection fraction was estimated 40-45% without significant valvular disease with high probability of pulmonary hypertension. Patient was immediately transported to clinical institution whit cardiac surgery capacity. VSD was repaired using pericardial patch. Patient recovered.

Conclusion: This case shows the importance of clinical examination and electrocardiographic with patients with non-specific symptoms. Mechanical complications of myocardial infarction are rare and unexpected particularly in patients who presents with non-specific symptoms. However, echocardiography, essential method for diagnosing mechanical complications, showed life threatening state of the patient.

LITERATURE

1 

Crenshaw BS, Granger CB, Birnbaum Y, Pieper KS, Morris DC, Kleiman NS, et al. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators. Circulation. 2000 January 4-11;101(1):27–32. https://doi.org/10.1161/01.CIR.101.1.27 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/10618300

2 

Elbadawi A, Elgendy IY, Mahmoud K, Barakat AF, Mentias A, Mohamed AH, et al. Temporal Trends and Outcomes of Mechanical Complications in Patients With Acute Myocardial Infarction. JACC Cardiovasc Interv. 2019 September 23;12(18):1825–36. https://doi.org/10.1016/j.jcin.2019.04.039 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/31537282

3 

Birnbaum Y, Fishbein MC, Blanche C, Siegel RJ. Ventricular septal rupture after acute myocardial infarction. N Engl J Med. 2002 October 31;347(18):1426–32. https://doi.org/10.1056/NEJMra020228 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/12409546


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