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Meeting abstract

https://doi.org/10.15836/ccar2024.609

The significance of echocardiography in oncology

Marija Antunović orcid id orcid.org/0009-0009-6583-6910 ; Dubrava University Hospital, Zagreb, Croatia
Jelena Miličević orcid id orcid.org/0009-0005-7453-0439 ; Dubrava University Hospital, Zagreb, Croatia
Ivica Benko orcid id orcid.org/0000-0002-1878-0880 ; Dubrava University Hospital, Zagreb, Croatia
Senka Pejković orcid id orcid.org/0000-0002-7557-9358 ; Dubrava University Hospital, Zagreb, Croatia


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Abstract

Keywords

echocardiography; cardio-oncology; guidelines; cardiotoxicity; cancer therapy

Hrčak ID:

328894

URI

https://hrcak.srce.hr/328894

Publication date:

13.12.2024.

Visits: 311 *



Over the past 30 years, the treatment of malignant diseases has made significant progress. Modern oncological therapies, including chemotherapy, radiotherapy, targeted therapies, and immunotherapy, have improved patient survival. Unfortunately, the treatment of malignancies has also led to an increase in adverse cardiovascular complications, which can negatively impact quality of life and survival. The cardiotoxic effects of oncological therapy can occur early or late after the initiation or completion of treatment. Their occurrence and intensity depend on the type of drug used, therapy combinations, radiotherapy, and pre-existing cardiovascular conditions. Due to the variability in the onset of negative effects on the heart, even years after treatment, and the increasing number of cancer treatment modalities, a new subspecialty—cardio-oncology—has developed to monitor and manage the impact and intensity of cardiotoxicity. Cardio-oncology plays a key role in addressing issues related to oncological treatments and heart health. According to the guidelines issued in 2022 by the European Society of Cardiology (ESC) for cardio-oncology, the aim is to assist all healthcare professionals providing care to cancer patients before, during, and after cancer treatment in terms of their cardiovascular health and well-being. (1) This highlights the importance of cardiac ultrasound in oncology and its crucial role in diagnosing cardiotoxicity. Three-dimensional (3D) echocardiography offers a more accurate way to measure left ventricular volumes, including left ventricular ejection fraction (LVEF), and has shown less variability in measurements compared to 2D methods. Therefore, 3D echocardiography should be used for serial monitoring of the cardiac effects of chemotherapy whenever possible. To understand the importance of more frequent monitoring of patients with echocardiography, it is essential to be familiar with how various cancer treatments affect the myocardium. (2,3)

LITERATURE

1 

Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, et al. ESC Scientific Document Group. 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). Eur Heart J. 2022 November 1;43(41):4229–361. https://doi.org/10.1093/eurheartj/ehac244 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/36017568

2 

Negishi T, Thavendiranathan P, Penicka M, Lemieux J, Murbraech K, Miyazaki S, et al. Cardioprotection Using Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy: 3-Year Results of the SUCCOUR Trial. JACC Cardiovasc Imaging. 2023 March;16(3):269–78. https://doi.org/10.1016/j.jcmg.2022.10.010 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/36435732

3 

Salte IM, Østvik A, Olaisen SH, Karlsen S, Dahlslett T, Smistad E, et al. Deep Learning for Improved Precision and Reproducibility of Left Ventricular Strain in Echocardiography: A Test-Retest Study. J Am Soc Echocardiogr. 2023 July;36(7):788–99. https://doi.org/10.1016/j.echo.2023.02.017 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/36933849


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