Veterinarski arhiv, Vol. 95 No. 2, 2025.
Izvorni znanstveni članak
https://doi.org/10.24099/vet.arhiv.2660
Efficient BVD control on large industrial dairy farms infected with different subtypes of Pestivirus A strains
Attila Dobos
; Ceva-Phylaxia Veterinary Biologicals Co. Ltd., Budapest, Hungary; Large Animal Clinical Laboratory, University of Veterinary Sciences, Faculty of Veterinary Medicine, Brno, Czech Republic
*
Krisztina Szigeti
; Ceva-Phylaxia Veterinary Biologicals Co. Ltd., Budapest, Hungary
Liliana Cubas-Gaona
; Ceva-Phylaxia Veterinary Biologicals Co. Ltd., Budapest, Hungary
Hágár Sasvári
; School of Infection and Immunity, University of Glasgow, Glasgow, UK
Marko Samardžija
; Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Mislav Kovačić
; Department of Biology, University of Osijek, Osijek, Croatia
István Kiss
; Ceva-Phylaxia Veterinary Biologicals Co. Ltd., Budapest, Hungary
* Dopisni autor.
Sažetak
Bovine viral diarrhea (BVD) is a major economically significant disease condition of cattle, occurring worldwide and caused by Pestivirus A, B, and rarely D viruses. Infection by the virus has a peculiar epidemiology that involves immunotolerant, persistently infected (PI) calves, which spread the virus lifelong in high amounts, and therefore finding and eliminating them is the cornerstone of most eradication programs, aided by provision of sufficient immune status for the dams to prevent the emergence of PI offspring. We demonstrate the efficient control of the prevailing Pestivirus A subtypes 1b, 1d, and 1f, in various Hungarian industrial dairy farms, by following the principles of bovine viral diarrhea virus (BVDV) eradication, such as screening the herds for the presence of and removal of PI animals, proper vaccination, and monitoring the BVDV status of the herds by laboratory testing. The tested partial Npro coding sequences indicated the presence of herd specific strains in each farm. The results confirmed that vaccination is a powerful tool for eradication of BVDV even if the live vaccine strain is heterologous compared to the field strains circulating on the affected farms.
Ključne riječi
dairy cattle; BVD; control; Npro sequence
Hrčak ID:
330424
URI
Datum izdavanja:
1.4.2025.
Posjeta: 769 *