Recenzija, prikaz
https://doi.org/10.3325/cmj.2023.64.362
Markers of cardiac injury in patients with liver cirrhosis
Stjepan Šimić
; Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Zagreb, Croatia
Tomo Svaguša
; Department of Cardiovascular Disease, Dubrava University Hospital, Zagreb, Croatia
*
Ivica Grgurević
; Department of Gastroenterology, Dubrava University Hospital, Zagreb, Croatia
Sanda Mustapić
; Department of Gastroenterology, Dubrava University Hospital, Zagreb, Croatia
Marko Žarak
; Clinical Department of Laboratory Diagnostics, Dubrava University Hospital, Zagreb, Croatia
Ingrid Prkačin
; Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia
* Dopisni autor.
Sažetak
Liver cirrhosis is an increasing public health problem and
a major cause of morbidity and mortality. Accordingly, cirrhotic cardiomyopathy, a frequently underdiagnosed condition, is becoming a growing health problem. In the last
20 years, cardioselective biomarkers have been investigated for their diagnostic and prognostic properties for numerous conditions. The aim of this article is to review the
literature on the relationship between the most commonly used cardioselective biomarkers (cardiac troponins I and
T, N-terminal pro-B-type natriuretic peptide, brain natriuretic peptide, and heart-type fatty-acid binding protein)
and the presence, functional stage, and clinical outcomes
of liver cirrhosis. Elevated plasma levels of these biomarkers have been reported in patients with liver cirrhosis, and
there is mounting evidence on their predictive value for
clinical outcomes in this disease. In addition, elevated plasma levels of these biomarkers have been reported in patients before, during, and after liver transplantation, but in
fewer studies. Due to their predictive value for clinical outcomes, we advocate the use of these markers in patients
with liver cirrhosis and cirrhotic cardiomyopathy, as well as
in candidates for liver transplant
Ključne riječi
Hrčak ID:
331875
URI
Datum izdavanja:
30.9.2024.
Posjeta: 35 *