Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2024.65.189
Pregnant couples’ attitude toward extended preconceptional genomic screening
Mojca Čižek Sajko
; Clinical Institute for Genomic Medicine, University Medical Center Ljubljana, Ljubljana, Slovenia
Bernarda Prosenc
; Clinical Institute for Genomic Medicine, University Medical Center Ljubljana, Ljubljana, Slovenia
Lovro Vidmar
; Clinical Institute for Genomic Medicine, University Medical Center Ljubljana, Ljubljana, Slovenia
Gordana Njenjić
; Clinical Department of Perinatology, Division of Gynecology and Obstetrics, University Medical Center Ljubljana, Ljubljana, Slovenia
Paula Duff
; Clinical Institute for Genomic Medicine, University Medical Center Ljubljana, Ljubljana, Slovenia
Borut Peterlin
; Faculty of Health Sciences, University of Novo Mesto, Slovenia
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* Dopisni autor.
Sažetak
Aim To determine the attitudes of pregnant couples toward carrier screening genomic tests.
Methods A validated 22-item questionnaire was offered
in person by medical staff to pregnant women ≥32 weeks’
gestation and their partners attending prenatal classes
from May to July 2014. The questionnaire inquired about
demographic data, interest in various forms of genetic carrier screening tests, and genetic literacy.
Results Of 497 respondents, 69% expressed strong interest in carrier screening. The interested respondents exhibited substantial support for screening for common (82%)
or all known genetic diseases (79%), as well as for treatable
(79%) and untreatable diseases (85%). The majority of respondents believed that genetic test results could provide
them with a sense of security but also provoke anxiety and
fear. They were aware that these results could affect their
perspective on life, work, and the atmosphere within their
family, and acknowledged the potential effect on their relationship with their partner. However, none of these concerns diminished their desire to learn about their carrier
status. Respondents with higher genetic literacy exhibited
greater interest in screening tests (P=0.006). More non-religious respondents compared with practicing religious respondents (P=0.002), and more respondents with higher
education compared with those with lower education, expressed interest in screening (P=0.003).
Conclusion Most respondents expressed considerable
interest in receiving information about their carrier status
through genetic tests.
Ključne riječi
Hrčak ID:
331954
URI
Datum izdavanja:
16.6.2024.
Posjeta: 0 *