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Study on the Lewis Acid-promoted Aza-Diels – Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones

Tanja Poljak ; Ruđer Bošković Institute, Zagreb, Croatia; GlaxoSmithKline Research Centre Zagreb Ltd., Zagreb, Croatia
Krešimir Molčanov ; Ruđer Bošković Institute, Zagreb, Croatia
Davor Margetić ; Ruđer Bošković Institute, Zagreb, Croatia
Ivan Habuš ; Ruđer Bošković Institute, Zagreb, Croatia


Puni tekst: engleski pdf 508 Kb

str. 539-558

preuzimanja: 932

citiraj


Sažetak

trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder
reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a
route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro-4-pyridones.

Ključne riječi

beta-lactam, imine, pyridone, aza-Diels – Alder reaction, Lewis acid

Hrčak ID:

31180

URI

https://hrcak.srce.hr/31180

Posjeta: 1.611 *