Original scientific paper
Seroprevalence of Helicobacter Pylori Infection in Dyspeptic Patients
Marinko Marušić
Vladimir Presečki
Miroslava Katičić
Ante Bilić
Dragan Jurčić
Dragan Schwarz
Abstract
The objective of the study was to assess the effect of age on the seroprevalence of Helicobacter (H.) pylori infection in
dyspeptic patients. The results obtained in the patient group were compared with findings on the seroprevalence of H.
pylori infection in 2051 blood donors. Serum samples were tested by the commercial ELISA and CFT assays according to
manufacturer’s instructions. The mean seroprevalence of H. pylori infection as determined by ELISA/CFT was 64.0%/
51.7% in the group of blood donors and 92.3%/89.5% in the group of dyspeptic patients. Study results indicated a higher
prevalence of H. pylori infection in dyspeptic patients as compared with blood donors in all age groups. In the patient
Sgroup, H. pylori seroprevalence was not age dependent.
Keywords
seroprevalence; Helicobacter pylori; dyspeptic patients; enzyme-linked immunosorbent assay (ELISA); complement fixation test (CFT)
Hrčak ID:
34298
URI
Publication date:
1.12.2008.
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