Prethodno priopćenje

Hodgkin’s Lymphoma Variant of Richter’s Syndrome

Ankica Vasilj ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Sandra Kojić-Katović ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Ivana Maričević ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Edita Žokvić ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Iva Bobuš Kelčec ; Department of Cytology, University Clinic for Tumors, Zagreb, Croatia
Davor Tomas ; University Department of Pathology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Silva Ćurić-Jurić ; Department of Cytology, University Clinic of Internal Medicine, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia

Sažetak

Chronic lymphocytic leukemia/small lymphocitic lymphoma (CLL/SLL) is low-grade malignant lymphoprolipheration, that has tendency to conwert to a higher-grade neoplasam over time. More common is the development of a diffuse large cell lymphoma or transformation into prolymphocytic cell population. In rare cases, 0.1–0.5% of patients develop multiple myeloma or Hodgkin’s disease. We present 65-year old female with Hodgkin’s variant of Richter’s syndrome. On the basis of clinical simptoms, cytological, hystological and immunohistological finding in April 2008 CLL/SLL were diagnosed. The patient was treated with 8 courses of R-CHOP. After 10 month, FNA of the one of the enlarged lymph node on the neck was performed. The diagnosis was Hodgkin’s disease. Immuno-hystological studies of the lymph node was consistent with type I Hodgkin’s type of Richter’s syndrome. Patient was treated with 3 courses of ABVD and radiotherap.

Ključne riječi

Richter’s syndrome; chronic lymphocytic leukemia; Hodgkin’s disease; Reed-Sternberg cell

Hrčak ID:

51282

URI

https://hrcak.srce.hr/51282

Datum izdavanja:

10.3.2010.

Posjeta: 1.799 *