Original scientific paper
Immunohistochemical Analysis of the Human Psoas Major Muscle with Regards to the Body Side and Aging
Juraj Arbanas
; Department of Anatomy, School of Medicine, University of Rijeka, Croatia
Gordana Starčević Klasan
; Department of Anatomy, School of Medicine, University of Rijeka, Croatia
Marina Nikolić
; Department of Anatomy, School of Medicine, University of Rijeka, Croatia
Olga Cvijanović
; Department of Anatomy, School of Medicine, University of Rijeka, Croatia
Daniela Malnar
; Department of Anatomy, School of Medicine, University of Rijeka, Croatia
Abstract
The aim of our study was to explore the age related changes of the fibre type composition of the human psoas major muscle. Moreover, we wanted to compare the fibre type composition of the left and right muscle. Muscle samples were collected from 15 young and 15 old males. Type I, IIA and IIX muscle fibres were typed using myosin heavy chain identification. The serial transverse sections were analysed using a light microscope. Results of our study showed that the age-related atrophy affected all three fibre types. Type IIA fibres were affected most profoundly while type I fibres were affected most weakly. The percentage of the different fibre types did not change during aging. There were no differences in the fibre type composition between the left and right muscle. Human psoas major muscle undergoes normal aging changes with the atrophy of all three fibre types, whereas atrophy most profoundly affects type IIA fibres. No differences in the fibre type composition between the left and right muscle point to the equal engagement of both legs in normal everyday activities of human.
Keywords
human; psoas major muscle; aging; left-right; myosin heavy chain; Immunohistochemistry
Hrčak ID:
51651
URI
Publication date:
20.4.2010.
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