Stručni rad
New Option in Photoprotection
Ines Sjerobabski Masnec
; Clinical Department of Dermatovenerology, University Hospital »Sestre milosrdnice«, Zagreb, Croatia
Lena Kotrulja
; Clinical Department of Dermatovenerology, University Hospital »Sestre milosrdnice«, Zagreb, Croatia
Mirna Šitum
; Clinical Department of Dermatovenerology, University Hospital »Sestre milosrdnice«, Zagreb, Croatia
Sanja Poduje
; Clinical Department of Dermatovenerology, University Hospital »Sestre milosrdnice«, Zagreb, Croatia
Sažetak
All the people are exposed to solar ultraviolet radiation. Exposure to sun with living in an oxygen-rich atmosphere causes unwanted photodemage. Sunburned skin is a leading risk factor for melanoma and non-melanoma cancers. UV exposure causes immunosuppression via multiple mechanisms in the skin. In this review the main topic is to mention new or alternative ways of photoprotection. Sunscreens are commonly used as protection against sun damage. They reduce the penetration of damaging solar UV wavelengths in skin by reflecting or absorbing them. Sunscreens are very valuable, but they have limitations. They have to be used properly to gain the full effect (application a little while before UV exposure, at frequent time points and in adequate amounts). Also, they have the problem of photoinactivation, which is the degeneration of the UV-filter due to exposure to UV rays resulting in the loss of absorbing capacity. Products with immune protection factor contain DNA-repair enzymes and antioxidants that may reduce mutations and enable the immune system to combat photodamage. The use of antioxidants and polyphenols may exert an anti-aging effect by preventing and even reversing sun damage. Adequate photprotection is essential to control photocarcinogenesis and photoaging.
Ključne riječi
photoprotection; UV radiation; DNA repair enzymes; polyphenols
Hrčak ID:
51670
URI
Datum izdavanja:
20.4.2010.
Posjeta: 1.537 *