Pregledni rad
A Case Report of an Unrecognized Nevoid Melanoma in a Young Woman – Clinicopathological Diagnostic Challenge
Marija Buljan
; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Vinogradska 29, 10 000 Zagreb, Croatia
Mirna Šitum
; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Vinogradska 29, 10 000 Zagreb, Croatia
Davor Tomas
; Department of Pathology, University Hospital »Sestre Milosrdnice«, Vinogradska 29, 10 000 Zagreb, Croatia
Vlatka Čavka
; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Vinogradska 29, 10 000 Zagreb, Croatia
Sanja Poduje
; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Vinogradska 29, 10 000 Zagreb, Croatia
Slavko Gašparov
; Department of Pathology and Cytology, Clinical Hospital »Merkur«, Zajčeva 19, 10 000 Zagreb, Croatia
Sažetak
Nevoid melanoma is a rare form of melanoma histologically resembling benign melanocytic nevi and may be overlooked in routine histological sections. Authors are presenting a case of a 31-year-old woman who presented with bizarre pigmented skin lesions in the area of the postoperative scar on the back where, 6 years earlier, a »nevus pigmentosus epidermo-dermalis« was excised and hystologically confirmed in outer institution. The lesions were surgically removed and histopathological findings were characteristic for nevoid melanoma. Additionally, specimen of primary removed lesion was reexamined and primary nevoid melanoma was then recognized, therefore indicating that the lesions our patient presented with are nevoid melanoma recidivisms. Extensive diagnostic procedures showed no signs of melanoma dissemination. Three months later, the patient returned for consultation and presented with two new brownish-pigmented papules n the area of the new postoperative scar. The lesions were excised and new nevoid melanoma recidivism was confirmed. The patient remained under the regular follow up and, almost 9 years after the removal of primary nevoid melanoma, followed by two cutaneous recidivisms, remains disease-free. This case aims to highlight the problematic area in the analysis of pigmented skin lesions where nevoid melanoma represents one of the clinical and pathological diagnostic challenges.
Ključne riječi
nevoid melanoma; melanoma; problematic melanocytic lesions
Hrčak ID:
51682
URI
Datum izdavanja:
20.4.2010.
Posjeta: 1.736 *