Pregledni rad

Clinical genetics and breast cancer

Gorazd Rudolf ; Institut za medicinsku genetiku, Ginekološka klinika, Ljubljana, Slovenija
Borut Peterlin orcid.org/0000-0001-7824-4978 ; Institut za medicinsku genetiku, Ginekološka klinika, Ljubljana, Slovenija

Sažetak

It is known that geneti c factors play an important role as risk factors in breast cancer. 5 to 10% of breast cancer is of monogenetic predispositi on. In the process of clinical evaluati on of pati ents with breast cancer it is very importnat to identify those pati ents with
high probability of having cancer predisposing mutati ons and to provide them relevant and professional genetic and clinical management. This can lead to the identification of genetic
etiology of breast cancer and allow earlier and more efficient prevention, screening and treatment of breast cancer.

Ključne riječi

BRCA1; BRCA2; breast cancer; DNA testing; genetic counseling

Hrčak ID:

53166

URI

https://hrcak.srce.hr/53166

Datum izdavanja:

7.6.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 3.197 *