Pregledni rad

Iron overload as a consequence of red blood cell transfusions in patients with hematological diseases

Toni Valković ; Zavod za hematologiju, reumatologiju i kliničku imunologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Duška Petranović ; Zavod za hematologiju, reumatologiju i kliničku imunologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Antica Načinović-Duletić ; Zavod za hematologiju, reumatologiju i kliničku imunologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Ivan Host ; Zavod za hematologiju, reumatologiju i kliničku imunologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska

Sažetak

Iron overload is a very common and serious complicati on of repeated red blood cell transfusions which contributes to organ dysfuncti on and influences survival in patients with hematological diseases. Several methods for measuring ti ssue iron content are used in every-day practice. Iron chelation therapy is recommanded when serum ferriti n levels reach 1000 ug/L and/or in pati ents who have previously received more then 20 units of red blood cell. Effective iron chelators are essenti al in the management of iron overload of hematological patients that require repeted blood transfusions with proved reducti on of morbidity and improvement of their quality of life.

Ključne riječi

blood transfusion; ferritin; iron; hematological diseases; iron chelators; iron overload

Hrčak ID:

53217

URI

https://hrcak.srce.hr/53217

Datum izdavanja:

7.6.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 3.768 *