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EOSINOPHILIA IN CHILDREN WITH ATOPIC ECZEMA/DERMATITIS SYNDROME

Slavica Dodig orcid.org/0000-0002-3419-5171 ; Dječja bolnica Srebrnjak
Miljenko Raos ; Dječja bolnica Srebrnjak
Renata Zrinski Topić orcid.org/0000-0002-3740-7854 ; Dječja bolnica Srebrnjak

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Sažetak

Atopic eczema/dermatitis syndrome (AEDS) is a chronic inflammatory skin disease, already manifested in infancy with major and minor features.
The aim was to investigate whether there is a difference between the number of eosinophil granulocytes in children with allergic atopic eczema/dermatitis syndrome (AAEDS) and non-allergic atopic eczema/dermatitis syndrome (NAAEDS), and to find the possible correlation between eosinophilia and the severity index of AEDS. The results have shown that the number of eosinophil granulocites was the highest in children with AAEDS with associated asthma and rhinitis (M = 705 x 106/L; IQR = 490 – 1030 x 106/L), and the lowest in children with NAAEDS (M = 290 x 106/L; IQR = 200 – 460 x 106/L). There was a correlation between eosinophils and the severity index in children with NAAEDS and in children with AAEDS without associated allergic respiratory diseases. This retrospective study has shown that eosinophilia was typical for both children with AAEDS and those with NAAEDS, respectively, and that the degree of eosinophilia was dependent on disease activity.

Ključne riječi

Descriptors: DERMATITIS, ATOPIC; EOSINOPHILIA; INFANT; CHILD, PRESCHOOL; CHILD

Hrčak ID:

57874

URI

https://hrcak.srce.hr/57874

Datum izdavanja:

15.5.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.327 *