Pregledni rad

Fixed Combinations

Diana Delić-Brkljačić ; KB "Sestre milosrdnice"

Sažetak

Fixed combinations of antihypertensive drugs simplify treatment and enhance patient compliance. They facilitate dosage and they are therefore better accepted by patients. Drug titration to optimal effects is simplified, which improves compliance and efficacy. The combination of drugs with complementary mechanisms of action may enhance useful effects of both components, while undesirable effects of highdose monotherapy may be reduced. In addition to blood pressure regulation, such combinations additionally decrease the rate of cardiovascular events, acting on the mechanisms causing the disease. The latest guidelines for the treatment of hypertension of the European Society of Hypertension and European Society of Cardiology (ESH/ESC) issued in 2007 and renewed in 2009, as well as the results of numerous new studies indicate the combinations of ACE inhibitors or angiotensin II receptor blockers with calcium-channel blockers or diuretics as combination therapies of choice.

Ključne riječi

hypertension; monotherapy; combination therapy; fixed therapy

Hrčak ID:

65109

URI

https://hrcak.srce.hr/65109

Datum izdavanja:

11.12.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 5.356 *