Review article

Granular Myoblastoma: A Case Presentation and Review of Literature

Irina Filipović-Zore
Sven Seiwerth
Spomenka Manojlović
Mato Sušić

Abstract

The paper describes the unusual localisation of a granular myoblastoma. Granular myoblastoma, or myoblastoma of granular cells, is a tumour of controversial etiology, and according to its rare occurrence in tissues, is an entity in itself. It occurs most frequently in subcutaneous tissues, skin, the breasts, skeletal muscles, and also intraoral tissues, where it occurs most often in the tongue.
In the presented case the tumour occurred on the upper lip, on the border of the lip redness, and after excisional biopsy granular cell myoblastoma was confirmed. According to all criteria the tumour histologically answered the description of the described tumour, and as it was also partially found subcutaneously, pseudoepitheliomatous hyperplasia of the epithelia had occurred. As the alteration was completely excised no further treatment was necessary, and two years after the operation there had been no recurrence.
The reasons for the development of this tumour and its histogenetic origin have still not been completely explained. However new immunocystochemical examinations tend to support the neural theory of its occurrence. Thus, this change should be kept in mind during differential diagnostics of changes which resemble mucocele, fibromas, pyogenous granulomas, papillomas, angiomas and planocellular carcinomas.

Keywords

myoblastoma of granular cells; upper lip; pseudoepitheliomatous hyperplasia

Hrčak ID:

11102

URI

https://hrcak.srce.hr/11102

Publication date:

15.6.2000.

Article data in other languages: croatian

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