Case report

Congenital nephroblastoma in a Holstein-Friesian fetus.

Rajamanickam Madheswaran ; Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Mahakrishnan Palanisamy ; Department of Animal Reproduction, Gynecology and Obstetrics, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Sakthivel Manokaran ; Department of Animal Reproduction, Gynecology and Obstetrics, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Soundarapandian Sivaseelan ; Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Gurusamypalayam A. Balasubramaniam ; Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Govindarajan Vijayakumar ; Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Mani Selvaraju ; Department of Clinics, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
Royappan E. Napolean ; Department of Animal Reproduction, Gynecology and Obstetrics, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India

Abstract

A seven-year-old Holstein-Friesian cow was brought to the hospital with signs of dystocia in the eighth month of gestation. The dystocia was relieved and a dead male fetus removed. The fetus had a significantly distended abdomen. At necropsy, the fetus showed a very large, round and well encapsulated extra renal mass in the abdominal cavity. The cut surfaces of the mass showed a white, caulifl ower-like growth with red surfaces. The lobules were spongy and distinctly demarcated by fat and hemorrhages. Microscopic examination of the tissue sections revealed blastemal, epithelial and mesenchymal elements. These cells were round to oval in shape with scanty cytoplasm. The nuclei were spherical, sometimes vesicular and hyperchromatic. The epithelial structures resembled the development of tubulo-glomerulogenesis. The mesenchymal cells were polyhedral in shape, found between the tubules. The gross and microscopic features of the tissue sections were consistent with a diagnosis of nephroblastoma.

Keywords

Holstein-Friesian fetus; nephroblastoma; gross pathology; histopatholog

Hrčak ID:

119061

URI

https://hrcak.srce.hr/119061

Publication date:

31.3.2014.

Article data in other languages: croatian

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