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The linkage between psoriasis and non-alcoholic fatty liver disease: a literature review
Andréia Nogueira Ramos
; Federal University of Bahia, Department of Dermatology
Bruno de Oliveira Rocha
; Federal University of Bahia, Department of Dermatology
Vitória Regina Pedreira de Almeida Rêgo
; Federal University of Bahia, Department of Dermatology
Ivonise Follador
; Federal University of Bahia, Department of Dermatology
Maria de Fátima Santos Paim de Oliveira
; Federal University of Bahia, Department of Dermatology
Abstract
Psoriasis is a chronic systemic inflammatory disease mainly affecting the skin. Population-based surveys have shown a higher prevalence of non-alcoholic fat liver disease (NAFLD) in patients with psoriasis compared with the general population, especially in those with a greater psoriasis area and severity index (PASI). It is speculated that similar pathogenic bases may play a role in this association, highlighting insulin resistance and the release of inflammatory cytokines as the most likely causes. In the present work, we review basic aspects of the relationship between psoriasis and NAFLD.
Keywords
psoriasis; non-alcoholic fatty liver disease; steatohepatitis
Hrčak ID:
125598
URI
Publication date:
28.7.2014.
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