Original scientific paper

Mammary gland tumours in male dogs: a hormonal and tumour marker study.

Swapan K. Maiti orcid.org/0000-0002-2593-012X ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Dileep K. M. Kumar ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Sandeep Kumar ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Ninu A. Ravindran ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Dayamon Mathew ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Sangeetha Palakkara ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Mohsina A. Muthalavi ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India
Naveen Kumar ; Department of Surgery, Indian Veterinary Research Institute, Izatnagar, India

Abstract

Seven male dogs with clinically and histologically confi rmed mammary gland tumours were included in this study. All dogs were sexually intact. Median age at diagnosis was 9.4 yrs. Five were purebred and the rest were mongrels. Six dogs had a solitary growth whereas in one animal multiple growths were seen. All tumours were histologically benign. Simple adenomas with mixed acinar and papillary pattern were observed. All tumours were removed surgically. Healing was perfect in all cases without any postoperative complications. No recurrence was recorded up to six months post-surgery. The expression of sex hormones and p53, cox-2 and MMP-7 tumour marker genes was strong in the majority of cases. Although uncommon, mammary tumours do occur in male dogs.

Keywords

dog; male; mammary tumour; surgery; tumour markers

Hrčak ID:

128662

URI

https://hrcak.srce.hr/128662

Publication date:

10.10.2014.

Article data in other languages: croatian

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