Original scientific paper

https://doi.org/10.5562/cca2381

Direct and Facile Synthesis of Acyl Isothiocyanates from Carboxylic Acids Using Trichloroisocyanuric Acid/Triphenylphosphine System

Najmeh Entezari ; Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran
Batool Akhlaghinia orcid.org/0000-0002-9940-5045 ; Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran
Hamed Rouhi-Saadabad ; Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran

Abstract

A mild, efficient, and practical method for one-step synthesis of alkanoyl and aroyl isothiocyanates from carboxylic acids using a safe and inexpensive mixed reagent, trichloroisocyanuric acid/triphenyl¬phosphine is described at room temperature. Availability of the reagents and easy workup of the reaction make this method attractive for organic chemists.

Keywords

acyl isothiocyanates; carboxylic acids; trichloroisocyanuric acid (TCCA); triphenylphosphine (TPP); potassium thiocyanate

Hrčak ID:

130427

URI

https://hrcak.srce.hr/130427

Publication date:

18.11.2014.

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