Original scientific paper

Regioselective Transesterifications of Cyclohexanone Derivatives Containing β-Keto and Malonic Ester Moieties

Janja Makarević ; Laboratory for Supramolecular and Nucleoside Chemistry, Department of Organic and Biochemistry, Ruđer Bošković Institute, P.O.B. 1016, 10001 Zagreb, Croatia
Mladen Žinić ; Laboratory for Supramolecular and Nucleoside Chemistry, Department of Organic and Biochemistry, Ruđer Bošković Institute, P.O.B. 1016, 10001 Zagreb, Croatia

Abstract

The cyclohexanone derivatives 1–6 containing β-ketoester and α-disubstituted malonic ester moieties in the same molecule were found to undergo regioselective transesterifications with benzyl alcohol giving exclusively β-keto benzyl esters. On the contrary, the acyclic derivatives 9, 10 containing β-ketoester and α-monosubstituted malonic ester groups gave mixtures of transesterified products under the same reaction conditions.

Keywords

Hrčak ID:

132408

URI

https://hrcak.srce.hr/132408

Publication date:

1.10.1998.

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