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Periodicum biologorum, Vol. 116 No. 4, 2014.

Short communication, Note

New primary non-breast malignancies after breast cancer: ten years single institution follow-up

Natalija Dedić Plavetić ; Department of Medical Oncology, 1_University Hospital Center Zagreb, Croatia; 2_University of Zagreb, School of Medicine, Croatia
Marina Barić ; Department of Medical Oncology, University Hospital Center Zagreb, Croatia
Paula Podolski ; Department of Medical Oncology, University Hospital Center Zagreb, Croatia
Tanja Badovinac-Črnjević ; Department of Medical Oncology, University Hospital Center Zagreb, Croatia
Damir Vrbanec ; Department of Medical Oncology, 1_University Hospital Center Zagreb, Croatia; 2_University of Zagreb, School of Medicine, Croatia

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Abstract

Background and Purpose: Breast cancer is the most common cancer in
Croatian women. Due to improved diagnostic and treatment options women with breast cancer now live longer, which increases their risk of developing new primary malignancies. The aim of this study was to establish incidence of new primary non-breast malignancies after breast cancer diagnosis.

Material and Methods: In the study cohort that included 215 consecutive patients treated for early breast cancer at University Hospital Center Zagreb, Croatia, 12 patients (5.58%) have developed new primary non-breast malignancy within nearly ten year follow-up.

Results: Although the majority of studies found gynecological cancers to be the most common cancer site of new primary non-breast malignancies after breast cancer diagnosis, in our study most patients developed colorectal cancer.

Conclusion: This is particularly interesting if you take into account that
after breast cancer colorectal cancer is the second most common cancer in Croatian women. In order to stratify the risk for the development of new primary tumors it is necessary to further investigate the interaction of various factors that are thought to influence the evolvement of tumors.

Keywords

breast cancer; new primary tumor

Hrčak ID:

138048

URI

https://hrcak.srce.hr/138048

Publication date:

30.12.2014.

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