Skip to the main content


Prolonged Activated Partial Thromboplastin Time: A Case Report

Petar Gaćina
Dubravka Čaržavec
Biserka Raić
Vladimir Stančić

Full text: english pdf 434 Kb

page 385-388

downloads: 587



A case of a 75-year-old female referred to our hospital for hip replacement with preoperative laboratory test of prolonged activated partial thromboplastin time due to factor XII deficiency is described. Other coagulation parameters known to be associated with prolonged activated partial thromboplastin time like factor VIII, factor IX, factor XI, high-molecular-weight kininogen and prekallikrein were normal, and there was no evidence for the presence of unspecified circulating anticoagulants or heparin. There is a general consensus that factor XII deficiency usually does not result in hemorrhagic diathesis. Its relationship with overt venous thrombosis is still unclear. The patient and her family had no history of bleeding disorder or thromboembolic events. There was no excessive bleeding or thromboembolic incident during the surgery and postoperative recovery.


Factor XII deficiency - etiology; Factor XII deficiency - complications; Factor XII deficiency - genetics; Blood coagulation disorders - complications

Hrčak ID:



Publication date:


Article data in other languages: croatian

Visits: 2.130 *