Acta clinica Croatica, Vol. 42 No. 4, 2003.
Other
Pancreatic Neuroendocrine Tumor Presenting with Carcinoid Syndrome: Case Report
Maja Berković
Vanja Zjačić-Rotkvić
Vesna Goldoni
Davor Hrabar
Nikola Karapandža
Abstract
Carcinoid is the most common neuroendocrine tumor. It is primarily localized in the ileum and the appendix, whereas other localizations are rare. Only a small number of the carcinoids present with carcinoid syndrome (flushing, diarrhea), usually after tumor has already metastasized. A case of carcinoid tumor of uncommon localization is reported. A 54-year-old male patient presented for evaluation because of weight loss, flushing and diarrhea. Laboratory value of 5-HIAA was 775.5 mmol/l (normal values up to 72.8) and the pancreatic tumor marker CA 19-9 was increased. Ultrasonographic and magnetic resonance find-Rings localized the tumor in the prepapillary pancreatic region and visualized the spread to the liver. The diagnosis was confirmed by pathohistologic evaluation of a liver biopsy specimen. The patient was treated with Sandostatin (octreotide analog), which led to significant relief of the symptoms, although control 5-HIAA values were not reduced.
Keywords
Neuroendocrine tumors, diagnosis; Pancreatic neoplasms, diagnosis; Pancreatic neoplasms, drug therapy; Carcinoid tumor, diagnosis; Carcinoid tumor, drug therapy; Case report
Hrčak ID:
14700
URI
Publication date:
1.12.2003.
Visits: 5.778 *