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Successful Management of a Chronic Refractory Leg Ulcer in an Adolescent with Sickle Cell Anemia
Giovanni Paolino
; La Sapienza University of Rome
Michelina Santopietro
Giovanna Palumbo
Maria Giuseppina Onesti
Alessandra Micozzi
Salvatore Venosi
Marica Laurino
Giancarlo Ferrazza
Pasquale Fino
Robin Foà
Fiorina Giona
Abstract
Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by a wide range of clinical manifestations. Chronic leg ulcers are a disabling complication with repercussions on the quality of life. We report the case of a 14-year-old girl with a diagnosis of SCD who developed a chronic leg ulcer that was successfully treated with a multi-disciplinary approach, including local and systemic therapies. The role of different treatments, in particular low molecular weight heparin, in the refractory chronic leg ulcer healing process will be discussed.
Keywords
sickle cell disease; chronic leg ulcer; hydroxyurea; NPWT therapy, low molecular weight heparin
Hrčak ID:
147147
URI
Publication date:
16.10.2015.
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