Short communication, Note
A selection of biological indicators in occupational exposure to toluene and xylene
Lj. Skender
; Institute for Medical Research and Occupational Health, Zagreb, Croatia
V. Karačić
; Institute for Medical Research and Occupational Health, Zagreb, Croatia
B. Bosner
; Institute for Medical Research and Occupational Health, Zagreb, Croatia
Abstract
Results of a comparative study of occupational exposure to toluene and xylene are presented. The study was carried out in a group of 24 workers from a paint factory and aimed to determine the most appropriate exposure indicators for use in biological monitoring. Measurements included toluene and xylene in blood and their metabolites in urine. Toluene in blood proved to be the best indicator of toluene exposure, and both xylene in blood and its only major metabolite methylhippuric acid in urine to be reliable indicators of xylene exposure, The validity of hippuric acid and o-cresol as toluene exposure indicators has not been confirmed.
Keywords
hippuric acid; methylhippuric acid; o-cresol; toluene in blood; xylene in blood
Hrčak ID:
147367
URI
Publication date:
14.7.1993.
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